Z-LLL-B(OH)2
MG-262 White solid. PROTECT FROM MOISTURE. A boronic acid-based, reversible proteasome inhibitor that is structurally similar to MG-132 (Cat. No. 474790) but displays much higher potency (Ki = 30 pM vs. 4 nM for MG-132). Purity: ≥95% by HPLC. Z-Leu-Leu-Leu-B(OH)2 Ref.: Adams, J., et al. 1998. Bioorg. Med. Chem. Lett. 8, 333. Mc Cormack, T., et al. 1997. J. Biol. Chem. 272, 26103. |
