Protein Phosphatase Inhibitor 2 Lyophilized solid. HYGROSCOPIC. Recombinant, human PPI2 expressed in E. coli. Inhibitor-2 is the regulatory subunit of the cytosolic type 1 Ser/Thr protein phosphatase-1 (PP1). It potently inhibits the activity of the free catalytic subunit of PP1 (IC50 = 1 nM). Purity: ≥95% by SDS-PAGE. M.W. 30,000 (by SDS-PAGE). Ref.: Yang, J., et al. 2000. J. Biol. Chem. 275, 22635. Huang, H.B., et al. 1999. J. Biol. Chem. 274, 7870. Helps, N.R., et al. 1994. FEBS Lett. 340, 93. Park, I., et al. 1994. J. Biol. Chem. 269, 944. Cohen, P. 1991. Methods Enzymol. 201, 389. |
