3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione Orange solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. An anilino-monoindolylmaleimide compound that acts as a potent and ATP-competitive inhibitor of PKCb isozymes (IC50 = 5 nM and 21 nM for human PKCbII and bI) and displays greater selectivity over PKCa, g,& e (IC50 = 331 nM, > 1 µM, and 2.8 µM, respectively). Purity: ≥90% by HPLC. CAS 257879-35-9. Ref.: Tanaka, M., et al. 2004. Bioorg. Med. Chem. Lett. 14, 5171. |
