InsR (1142-1153)
Protein Tyrosine Phosphatase Substrate II
TRDIpYETDpYpYRK Lyophilized. Supplied as a trifluoroacetate salt. HYGROSCOPIC. An excellent protein tyrosine phosphatase substrate. The sequence is derived from the insulin receptor b-subunit cytoplasmic domain containing the regulatory autophosphorylation sites Tyr1146, Tyr1150, and Tyr1151. Purity: ≥98% by HPLC. Sold on the basis of peptide content. H-Thr-Arg-Asp-IIe-Tyr(PO3H2)-Glu-Thr-Asp-Tyr(PO3H2)-Tyr(PO3H2)-Arg-Lys-OH Ref.: Keane, N.E., et al. 1994. Eur. J. Biochem. 226, 525. White, M.F. and Kahn, C.R. 1994. J. Biol. Chem. 269, 1. Cho, H., et al. 1993. Prot. Science 2, 977. |
