a-Bromo-4-hydroxyacetophenone
4-Hydroxyphenacyl Br
Protein Tyrosine Phosphatase Inhibitor I White powder. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent, cell-permeable, and covalent protein tyrosine phosphatase (PTP) inhibitor. Inhibits SHP-1 (DSH2), the catalytic domain of the SH2 domain-containing phosphatase SHP-1 (Ki = 43 µM), and PTPIB (Ki = 42 µM). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. Purity: ≥95% by HPLC. CAS 2491-38-5. Ref.: Arabaci, G., et al. 1999. J. Am. Chem. Soc. 121, 5085.
R: 34-36/37; S: 26-27-28-36/37/39 |
