1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide Virazole White solid. HYGROSCOPIC. A non-interferon-inducing, broad spectrum antiviral nucleoside. Reported to be active against RSV, HIV, HCV, and other infectious agents. Its metabolite, ribavirin-5′-phosphate, inhibits inosine monophosphate (IMP) dehydrogenase. Purity: ≥99% by HPLC, ≥99% by TLC. RTECS XZ4250000, CAS 36791-04-5. Merck Index: 14, 8198 Ref.: Li, W., et al. 1999. Oncol. Res. 11, 243. Honda, Y., et al. 1994. Antimicrob. Agents Chemother. 38, 653. Liao, H.J. and Stollar, V. 1993. Antiviral Res. 22, 285. Kakumu, S., et al. 1993. Gastroenterology 105, 507. Sidwell, R.W., et al. 1979. Pharmacol. Ther. 6, 123. R: 61; S: 3/7/9-22-45-53 |