3-(4-Methylpiperazinyliminomethyl)rifamycin SV
Rifampin

Brick red solid. Antibiotic that specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode. Purity: ≥97% by HPLC (dry basis). Contaminants: Heavy metals: ≤20 ppm. RTECS VJ7000000, CAS 13292-46-1.

Merck Index: 14, 8216
Ref.: Jin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72. Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277. Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.
R: 20/21/22-36/37/38-60-63; S: 36/37/39-45-53