4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone White solid. A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 800 nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Purity: ≥98% by HPLC. RTECS UY5749237, CAS 61413-54-5. Merck Index: 14, 8251
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