Tan solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A mitochondrial toxin and a potent, reversible, and competitive inhibitor of complex I (NADH-CoQ reductase) of the respiratory chain. Also inhibits cellular proliferation in mouse liver. Purity: ≥98% by TLC. RTECS DJ2800000, CAS 83-79-4. Merck Index: 14 8271 Ref.: Kopustinskiene, D.M., et al. 2001. Eur. J. Pharmacol. 428, 311. Higgins, D.S., Jr. and Greenamyre, J.T. 1996. J. Neurosci. 16, 3807. Cunningham, M.L., et al. 1995. Cancer Lett. 95, 93. R: 25-36/37/38-50/53; S: 22-24/25-36-45-60-61 |