Ammoniated Ruthenium Oxychloride RR Red-black solid. PROTECT FROM MOISTURE. A blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM). Ruthenium: ≥35% CAS 11103-72-3. Merck Index: 14, 8300 Ref.: Merck Index 13, 8379. Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656. Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082. Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940. Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225. Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651. Ma, J. 1993. J. Gen. Physiol. 102, 1031. R: 22; S: 22 |