Return to our Home Page

Tech Resources
Data Sheet
MSDS - English
Other Languages
Selected Citations
Certificate of Analysis
Store
-20°C-20°C
Ship
Shipped with Blue Ice <br> Shipped with blue ice (water ice)!Blue ice
FlammableFlammable
Note: Store and Ship conditions may differ.
See Key
PubChem
SID: 26759483

Inhibitor Database

Inhibitor Email Sign Up

Inhibitor Resource
   
Quick Order Shopping Cart
Email a Link to this Page Help
  InSolution™ SB 203580
Cat. No. 559398  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)

Liquid. A 1 mg/ml solution of SB 203580 (Cat. No. 559389) in anhydrous DMSO. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: ≥98% by HPLC.

Ref.: Powell, D.J., et al. 2003. Mol. Cell Biol. 23, 7794. Davies, S.P., et al. 2000. Biochem. J. 351, 95. Iwasaki, S., et al. 1999. J. Biol. Chem. 274, 26503. Gallagher, T.F., et al. 1997. Bioorg. Med. Chem. 5, 49. LoGrasso, P.V., et al. 1997. Biochem. 36, 10422. Hazzalin, C.A., et al. 1996. Curr. Biol. 6, 1028. Kramer, R.M., et al. 1996. J. Biol. Chem. 271, 27723. Saklatvala, J., et al. 1996. J. Biol. Chem. 271, 6586. Cuenda, A., et al. 1995. FEBS Lett. 364, 229. Gallagher, T.F., et al. 1995. Bioorg. Med. Chem. Lett. 5, 1171. Lee, J.C., et al. 1994. Nature 372, 739.
R: 36/37/38-40; S: 24/25-26-36/37/39-45

Need additional information about this product? Email our Technical Service department at: technical@calbiochem.com

 Related information for this product is available:
Additional information is available from the "Tech Resources"
box in the upper left panel of this page.

EMD Chemicals Inc. USD list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

Size
In Stock
Qty
Select Country Above
For Pricing Information
1 mlY$134.00


SolubilityMolecular FormulaMol. Wt.
 C21H16FN3OS 377.4 


Related Literature:

Protein Kinase and Related Tools Brochure
Inhibitor Sourcebook

Material Safety Data Sheets:
559398: InSolution™ SB 203580 - English
Bulgarian
Danish
Dutch
Finnish
French
German
Greek
Hungarian
Italian
Korean
Norwegian
Polish
Portuguese
Spanish
Swedish

Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)

Selected Citations:
  1. Alexandra Thiel, et al. (2006) Expression of Cyclooxygenase-2 Is Regulated by Glycogen Synthase Kinase-3beta in Gastric Cancer Cells. Journal of Biological Chemistry 281, 4564-4569.
  2. Bysani Chandrasekar, et al. (2005) The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-J. Journal of Biological Chemistry 280, 26263-26277.
  3. Guadalupe Sabio, et al. (2005) p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. The EMBO Journal 24, 1134-1145.
  4. Jose G. Trevino, et al. (2005) Expression and activity of Src regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis. Cancer Research 65, 7214-7222.
  5. Wojciech Wojciechowski, et al. (2005) Enhanced Expression of CD20 in Human Tumor B Cells is Controlled Through ERK-Dependent Mechanisms. Journal of Immunology 174, 7859-7868.
  6. Yung-Luen Yu, et al. (2005) MAP kinase-mediated phosphorylation of GATA-1 promotes Bcl-XL expression and cell survival. Journal of Biological Chemistry 280, 29533-29542.
  7. Naoto Inukai, et al. (2004) A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis. Journal of Biological Chemistry 279, 8190-8195.
 
Change Country | Contact Us | Privacy Policy | Terms and Conditions
 
©2008 Calbiochem, Novabiochem, & Novagen
are brands of EMD Chemicals Inc., an Affiliate of Merck KGaA, Darmstadt, Germany.