4-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-5-(4-pyridyl)-1H-imidazole Pale yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. The sulfone analog of the p38 MAP kinase inhibitor SB 203580 (Cat. No. 559389). Potently inhibits p38 kinase (IC50 = 30 nM) and inhibits IL-1 production in human monocytes (IC50 = 200 nM). Purity: ≥98% by HPLC. CAS 152121-46-5. Ref.: Gallagher, T.F., et al. 1997. Bioorg. Med. Chem. 5, 49. | 
