4-Ethyl-2(p-methoxyphenyl)-5-(4′-pyridyl)-IH-imidazole, DiHCl Yellow solid. PROTECT FROM LIGHT. HYGROSCOPIC. A water-soluble form of SB 202474 (Cat. No. 559387). Useful as a negative control for SB202190, HCl (Cat. No. 559393) and SB203580, HCl (Cat. No. 559395) in p38 MAP kinase inhibition studies. Purity: ≥97% by HPLC. Ref.: Cocolakis, E., et al. 2001. J. Biol. Chem. 276, 18430. Ho, A.K., et al. 2001. Biochem. Pharmacol. 62, 1605. Yu, R., et al. 2001. J. Biol. Chem. 275, 2322. Lee, J.C., et al. 1994. Nature 372, 739. |
