Host: Mouse

Isotype: IgG1

Immunogen: purified canine cardiac sarcoplasmic reticulum

Form: Liquid

Formulation: Ascites diluted in PBS.

Preservative: ≤0.1% sodium azide

Positive Control: Brain tissue (cerebrum and cerebellum)

Comments: Recognizes the ~100 kDa SERCA2 ATPase in type I (slow) skeletal and cardiac muscle. Recognizes rat SERCA2 ATPase only by immunohistochemistry. Also recognizes SERCA2 ATPase from rabbit stomach smooth muscle, porcine liver, and SERCA2b ATPase from the cerebrum and cerebellum of both rat and pig.

Ref.: Sharp, A.H., et al. 1993. J. Neuroscience 13, 3051. Spencer, G.G., et al. 1991. Biochim. Biophys. Acta 1063, 15. Molnar, E., et al. 1990. Biochim. Biophys. Acta 1023, 147. Jorgensen, A.O., et al. 1988. Cell Motil. Cytoskeleton 9, 164.