(2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam Orange solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCa) that efficiently enhances non-amyloidogenic a-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. Displays a marked loss of tumor promoting activity. Purity: ≥95% by HPLC. CAS 497259-23-1. Ref.: Kozikowski, A.P., et al. 2003. J. Med. Chem. 46, 364. | 
