Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable structural isomer of SIRT2 Inhibitor, AGK2 (Cat. No. 566324) that selectively inhibits sirtuin 3 over sirtuins 1 and 2 (IC50 = >5 µM, >50 µM and >50 µM for SIRT3, SIRT1 and SIRT2, respectively) and poorly affects both a-synuclein-mediated toxicity and a-Syn aggregation in a-Syn-H4 cells. Purity: ≥97% by HPLC. CAS 304896-21-7. Ref.: Outerio, T.F., et al. 2007. Science 317, 516. S: 22-24/25 |