Antimony Sodium Gluconate
NaSbv
SSG White solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. A pentavalent antimony compound that irreversibly inhibits protein tyrosine phosphatase (PTPase) activity, including Src homology PTPase-1 (SHP-1) (99% inhibition at ~11 µM) by forming a stable complex. At higher concentrations (~110 µM), it inhibits SHP-2 and PTP1B activities. Purity: ≥90% by titration on dry basis (≥30% Sb content). CAS 16037-91-5. Merck Index: 14, 701
Ref.: Wortmann, G., et al. 2002. Clin. Infect. Dis. 35, 261. Pathak, M.K. and Yi, T. 2001. J. Immunol. 167, 3391. |
