White solid. Antibiotic effective against Gram-positive and Gram-negative bacteria. Often used in culture media to control growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code. Activity: ≥700 U/mg. RTECS WK4990000, CAS 3810-74-0. Merck Index: 14, 8826 Ref.: Lech, K. and Brent, R. 1995. in Current Protocols in Molecular Biology, Vol. 1 (Ausubel, F.M., et al., eds.), John Wiley & Sons, New York Unit 1.4. Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York, p. A.6. Modolell, J. and Davis, B.D. 1969. Nature 224, 345. R: 22-61; S: 22-36/37/39-45 |