H-YGRKKRRQR-G-FCDGFYACYKDV-OH, Cyclic
P3-anti-HER-2/neu peptide mimetic Lyophilized. Supplied as a trifluoroacetate salt. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. The cell-permeant peptide carrier that has been used successfully to target ErbB2-overexpressing cancer cells. The carrier construct is composed of a 9-aa TAT-derived internalization sequence (P3), a glycine spacer, and a 12-aa anti-HER-2/neu peptide mimetic (AHNP). An essential control for P3-AHNP-based deliveries, such as studies that utilize P3-AHNP-STAT3BP (Cat. No. 573092). Purity: ≥97% by HPLC. H2N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Gly-Phe-Cys-Asp-Gly-Phe-Tyr-Ala-Cys-Tyr-Lys-Asp-Val-CO2H, Cyclic Ref.: Tan, M., et al. 2006. Cancer Res. 66, 3764.
Sold under license of U.S. Patent 7,179,785. |
