N-(3′,4′,5′,-Trimethoxybenzoyl)-(3,4-dimethoxy)ethylanthranilate Off-white solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A diaryl amide analog that exhibits about 15 fold greater selectivity in inhibiting the proliferation of human coronary artery smooth muscle cells (IC50 = 310 nM) over the endothelial cells (IC50 = 4.6 µM). Exhibits over 80-fold greater potency than Tranilast (Cat. No. 616400). Purity: ≥95% by HPLC. Ref.: Ogita, H., et al. 2001. Bioorg. Med. Chem. Lett. 11, 549.
R: 20/21/22; S: 36 |
