| Note: 1 T = 1 test. | | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Ser214 phosphorylation site of human Tau | | Form: Liquid | | Formulation: In Dulbecco's PBS (without Mg2+ and Ca2+), pH 7.3 (+/- 0.1), 50% glycerol, 1 mg/ml BSA (IgG, protease free). | | Preservative: ≤0.1% sodium azide | | Positive Control: Human recombinant tau treated with GSK-3b | | Comments: Recognizes the ~45-68 kDa Tau protein phophorylated at Ser214. | | Ref.: del C. Alonso, A., et al. 2001. J. Biol. Chem. 276, 37967. Sawamura, N., et al. 2001. J. Biol. Chem. 276, 10314. Bennecib, M., et al. 2000. FEBS Lett. 485, 87. Jenkins, S.M., et al. 2000. Biochem. J. 345, 263. Maas, T., et al. 2000. J. Biol. Chem. 275, 15733. Tesseur, I., et al. 2000. Am. J. Pathol. 156, 951. Jicha, G.A., et al. 1999. J. Neurosci. 19, 7486. Schneider, A., et al. 1999. Biochemistry 38, 3549. Hoffmann, R. et al. 1997. Biochemistry 36, 8114. Kopke, E., et al. 1993. J. Biol. Chem. 268, 24374. Arigada, P.A., et al. 1992. Neurology 42, 631. Drubin, D.G. and Kirschner, M.W. 1986. J. Cell. Biol. 103, 2739. | |