| Note: 1 T = 1 test. | | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Ser262 phosphorylation site of human Tau | | Form: Liquid | | Formulation: In PBS, 1 mg/ml BSA, 50% glycerol, pH 7.3. | | Preservative: ≤0.1% sodium azide | | Positive Control: Human recombinant tau treated with GSK-3b or OV-1 cells stably expressing human four-repeat tau and SV40 small Tantigen. | | Comments: Recognizes the ~45-68 kDa Tau protein phosphorylated at Ser262. | | Ref.: Bennecib, M., et al. 2001. FEBS Lett. 490, 15. del C. Alonso, A., et al. 2001. J. Biol. Chem. 276, 37967. Sawamura, N., et al. 2001. J. Biol. Chem. 276, 10314. Bennecib, M., et al. 2000. FEBS Lett. 485, 87. Hashiguchi, M., et al. 2000. J. Biol. Chem. 275, 25247. Jenkins, S.M., et al. 2000. Biochem. J. 345, 263. Jenkins, S.M., and Johnson, G.V. 2000. J. Neurochem. 74, 1463. Maas, T., et al. 2000. J. Biol. Chem. 275, 15733. Tesseur, I., et al. 2000. Am. J. Pathol. 156, 951. Schneider, A., et al. 1999. Biochemistry 38, 3549. Sengupta, A., et al. 1998. Arch. Biochem. Biophys. 357, 299. Wang, J.G., et al. 1998. FEBS Lett. 436, 28. Kopke, E., et al. 1993. J. Biol. Chem. 268, 24374. Arigada, P.A., et al. 1992. Neurology 42, 631. Drubin, D.G. and Kirschner, M.W. 1986. J. Cell. Biol. 103, 2739. | |