| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Ser422 phosphorylation site of human Tau | | Form: Liquid | | Formulation: In Dulbecco's PBS (without Mg2+ and Ca2+), 1 mg/ml BSA, 50% glycerol, pH 7.2-7.4. | | Preservative: ≤0.1% sodium azide | | Positive Control: CV-1 cells stably expressing four-repeat tau and SV40 small T antigen | | Comments: Recognizes the ~45-68 kDa tau protein phosphorylated at Ser422. | | Ref.: Bennecib, M., et al. 2001. FEBS Lett. 490, 15. del C. Alonso, A., et al. 2001. J. Biol. Chem. 276, 37967. Sawamura, N., et al. 2001. J. Biol. Chem. 276, 10314. Bennecib, M., et al. 2000. FEBS Lett. 485, 87. Hashiguchi, M., et al. 2000. J. Biol. Chem. 275, 25247. Jenkins, S.M., et al. 2000. Biochem. J. 345, 263. Maas, T., et al. 2000. J. Biol. Chem. 275, 15733. Schneider, A., et al. 1999. Biochemistry 38, 3549. Sengupta, A., et al. 1998. Arch. Biochem. Biophys. 357, 299. Wang, J.G., et al. 1998. FEBS Lett. 436, 28. Reynolds, C.H., et al. 1997. J. Neurochem. 68, 1736. Reynolds, C.H., et al. 1997. J. Neurochem. 69, 191. Kopke, E., et al. 1993. J. Biol. Chem. 268, 24374. Arigada, P.A., et al. 1992. Neurology 42, 631. Drubin, D.G. and Kirschner, M.W. 1986. J. Cell. Biol. 103, 2739. |
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