7-(2′,3′′-Dihydroxypropyl carbonoxy)paclitaxel White solid. HYGROSCOPIC. A prodrug of the anticancer agent Paclitaxel (Cat. No. 580555) that displays 50-fold higher water solubility than the parental drug; it is converted to Paclitaxel by pH-dependent hydrolysis. Shows significantly improved antitumor activity in mice compared to Paclitaxel (Cat. No. 580555). Purity: ≥98% by HPLC. Ref.: Niethammer, A., et al. 2001. Bioconjugate Chem. 12, 414. R: 37/38-41-46-60; S: 22-26-36/37/39-45 |