5′-d(TTAGGG)-3′
TAG-6 Lyophilized. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg. M.W. ~1900. 5'-d(TTAGGG)-3' Ref.: Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.
R: 20/21/22-40; S: 22-36 |
