4-Hydroxy-TEMPO
4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl Orange solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties. Purity: ≥98% by HPLC. RTECS TN8991000, CAS 2226-96-2. Ref.: Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633. Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103. Mota-Filipe, H., et al. 1999. Shock 12, 255.
R: 22-41; S: 39-26 |
