Yellow crystalline solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Broad-based antibiotic agent that blocks protein synthesis by inhibiting binding of aminoacyl tRNA to the A-site of ribosomes. Induces cold shock-response and enhances P450 expression in bacteria. Activity: ≥900 µg/mg. RTECS QI9100000, CAS 64-75-5. Merck Index: 14, 9196 Ref.: Kusano, K., et al. 1999. Arch. Biochem. Biophys. 367, 129. Lech, K. and Brent, R. 1995. In Current Protocols in Molecular Biology, Vol. 1 (Ausubel, F.M., et al. eds.) John Wiley & Sons, New York Unit 1.4. Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York, p. 1.6, A.6. Chopra, I. and Howe, T.G.B. 1978. Microbiol. Rev. 42, 707. R: 63; S: 36/37 |