Lyophlized. Lyophilized from 600 mM NaCl, 20 mM Tris, 1 mM CaCl₂, 20% sucrose, pH 7.8. Native thrombospondin purified from human platelets. Adhesive glycoprotein released in response to platelet activation by a-thrombin. An angiogenesis inhibitor that blocks the FGF-induced neovascularization of the rat cornea. An inducer of platelet aggregation. Synthesized by a number of different cells and secreted into the extracellular matrix. Involved in the regulation of cellular proliferation. Purity: ≥95% by SDS-PAGE. Prepared from platelets that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Merck Index: 14 9387
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