hTBG Liquid. In 140 mM NaCl, 10 mM Tris, 0.1% NaN3, pH 8.0. Sterile-filtered. Native, human thyroxine-binding globulin. Liver glycoprotein and a major thyroid hormone carrier in serum. Exhibits high sequence similarity with a1-antitrypsin. Its affinity for the hormone is thought to be temperature-sensitive. Purity: ≥99% by SDS-PAGE. Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. M.W. 54,000-64,000. Ref.: Miura, Y., et al. 1993. Endocrinol. J. 40, 127. Janssen, O.E., et al. 1992. J. Biol. Chem. 267, 13998. |
