3-(1-Anilinoethylidene)-5-benzylpyrrolidine-2,4-dione Solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A synthetic antitumor drug that blocks microtubule assembly and colchicine binding to tubulin. Prevents the stabilization of microtubules in Paclitaxel (Cat. No. 580555) -treated cells. Also blocks the cell cycle in M phase. Purity: ≥97% by TLC. CAS 33016-12-5. Ref.: Yamaguchi, Y., et al. 1995. Cell Struct. Funct. 20, 47. Gupta, R.S. 1986. Mol. Pharmacol. 30, 142. Roach, M.C. and Luduena, R.F. 1985. Biochem. Biophys. Res. Commun. 129, 200. Arai, T. 1983. FEBS Lett.155, 273.
R: 40; S: 36-22 |
