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  TRAIL, Human, Recombinant, E. coli
Cat. No. 616374  
All Categories » Calbiochem » Proteins and Enzymes » Apoptotic Pathway Proteins » TRAIL

Apo2L, Human, Recombinant, E. coli
TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli

Liquid. In 500 mM NaCl, 10 mM Na2HPO4, 2.7 mM KCl, 2 mM KH2PO4, 0.1 mM DTT, ≤10% glycerol. AVOID FREEZE/THAW CYCLES. Recombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues. Biological activity: Induces apoptosis in U937 cells at 1 mg/ml within 5 h.. Purity: ≥95% by SDS-PAGE. Contaminants: endotoxin <0.1 EU/µg TRAIL.

Ref.: Lin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638. Mitsaides, N., et al. 2000. Cancer Res. 60, 4122. Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343. Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221. Pan, G., et al. 1997. Science 276, 111. Pan, G., et al. 1997. Science 277, 815. Sheridan, J.P., et al. 1997. Science 277, 818. Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687. Wiley, S.R., et al. 1995. Immunity 3, 673.

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SolubilityMolecular FormulaMol. Wt.
  18000 

Related Literature:

Biologics 32.4

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616374: TRAIL, Human, Recombinant, E. coli - English
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All Categories » Calbiochem » Proteins and Enzymes » Apoptotic Pathway Proteins » TRAIL