ADAM-17 Substrate II, Fluorogenic
DABCYL-LAQAVRSSSR-EDANS
TNF-a Convertase Enzyme Substrate II, Fluorogenic Red lyophilized solid. PROTECT FROM LIGHT. A fluorescence resonance energy transfer (FRET) peptide substrate for TACE (Km = 19 µM). Substrate cleavage occurs at the Ala-Val bond. Useful for the screening of TACE and SARS protease 3-CLPRO inhibitors. Purity: ≥95% by HPLC. Excitation max.: ~340 nm, Emission max.: ~490 nm DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS Ref.: Bacha, U., et al. 2004. Biochemistry 43, 4906. Patel, I.R., et al. 1998. J. Immunol. 160, 4570. | 
