hTGF-b1 Transforming Growth Factor-b1 Lyophilized. Lyophilized from a sterile-filtered solution of 50 µg BSA/µg TGF-b1, 35% acetonitrile, 0.1% TFA. AVOID FREEZE/THAW CYCLES. Native transforming growth factor-b1 from human platelets. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Biological activity: ED50 = 40-10 pg/ml as measured by the inhibition of IL-4-dependant proliferation of mouse HT-2 cells using resazurin dye as an indicator of cell proliferation.. Purity: ≥97% by SDS-PAGE. Contaminants: Endotoxin: ≤1 EU/ug of TGF-b1. Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. Merck Index: 14, 9572 Ref.: Lomo, J., et al. 1995. J. Immunol. 154, 1634. Marushige, K. and Marushige, Y. 1995. Anticancer Res. 14, 2419. Bermundez, L.E. 1993. J. Immunol. 150, 1838. Hamilton, J.A., et al. 1993. J. Immunol. 150, 1496. Reilly, J.T., et al. 1993. Br. J. Haematol. 83, 58. Sporn, M.B. and Roberts, A.B. 1993. Growth Factors 8, 1. |