rhTGF-b1 Transforming Growth Factor-b1 Lyophilized. Lyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-b1, 35% acetonitrile, 0.1% TFA. Recombinant, human transforming growth factor-b1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases. Biological activity: ED50 = 0.04-0.1 ng/ml. Purity: ≥97% by SDS-PAGE. Contaminants: Endotoxin: ≤1 EU/µg TGF-b1. Merck Index: 14, 9572 Ref.: Shibuya, H., et al. 1996. Science 272, 1179. Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA 93, 5877. Lomo, J., et al. 1995. J. Immunol. 154, 1634. Marushige, K., and Marushige, Y. 1995. Anticancer Res. 14, 2419. Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221. |