2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline, HCl
SU 1433 Pale brown solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent and specific inhibitor of the PDGF-b receptor kinase (IC50 = 5.0 µM) and of KDR/Flk-1/VEGF Receptor 2 (IC50 = 9.3 µM). Also acts as an angiogenesis inhibitor. Purity: ≥95% by HPLC. Ref.: Kroll, J., and Waltenberger, J. 1997. J. Biol. Chem. 272, 32521. Strawn, L.M., et al. 1996. Cancer Res. 56, 3540. |
