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Inhibitor Libraries
  U0124
Cat. No. 662006  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)

1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene

White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A useful negative control for MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK activity even at concentrations of 100 µM. Purity: ≥95% by HPLC.

Ref.: Favata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.

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1 mgYN/A

SolubilityMolecular FormulaMol. Wt.
DMSO C8H10N4S2 226.3 


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Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)

Selected Citations:
  1. Neelakandan Muthukumaran, et al. (2006) Tumor necrosis factor-α differentially modulates CD44 expression in ovarian cancer cells. Molecular Cancer Research 4, 511-520.