SUMO-conjugating enzyme, Human, Recombinant, S. frugiperda

Liquid. In 125 mM NaCl, 50 mM HEPES, 1 mM DTT, 10% glycerol, pH 7.6. AVOID FREEZE/THAW CYCLES. Recombinant, human UbcH9 conjugating enzyme expressed in S. frugiperda insect cells. UbcH9 is a member of the E2 family of ubiquitin conjugating enzymes that is specific for the conjugation of SUMO-1, SUMO-2, and SUMO-3 to a variety of proteins including RanGAP1, IkBa and PML. It interacts directly with proteins that are modified by SUMOylation and may be important for substrate recognition. Purity: ≥98% by SDS-PAGE.

Ref.: Ito, K., et al. 2001. Eur. J. Biochem. 268, 2725. Ito, K., et al. 1999. Cytogenet. Cell. Genet. 84, 99. Kimura, M., et al. 1997. Cytogenet. Cell. Genet. 78, 107.