1a-OH-D2 White crystalline solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A vitamin D2 analog with potential for the treatment of secondary hyperparathyroidism and metabolic bone disease. May be an effective and safer alternative to Calcitriol (1a,25-Dihydroxyvitamin D3; Cat. No. 679101) for suppressing PTH without causing hypercalcemia. Metabolized in vivo to the natural active dihydroxylated metabolite of vitamin D2, 1a,25-dihydroxyvitamin D2. Purity: ≥98% by HPLC. RTECS VS2950000, CAS 54573-75-0. Ref.: Coburn, J.W., et al. 1996. Nephrol. Dial. Transplant. 11 (Suppl. 3), 153. Knutson, J.C., et al. 1995. Endocrinology 136, 4749.
R: 28-63; S: 22-36/37/39-45 |
