Anti-L-Type Ca²⁺ Channel

Host: Rabbit

Isotype: IgG

Immunogen: a synthetic peptide [(C)TTKINMDDLQPSENEDKS] corresponding to amino acids 818-835 of a1C-subunit of rat brain voltage-gated calcium channels, conjugated to KLH

Form: Lyophilized

Formulation: 50 µl antibody in PBS, 5% sucrose, 1% BSA, pH 7.4 and 40 µg lyophilized control peptide (immunogen).

Preservative: None

Positive Control: Rat brain or heart

Comments: Recognizes the ~190 kDa and ~210 forms of the a1C-subunit. Supplied with a control peptide. Note: The a-subunit is highly sensitive to proteases. Please refer to the data sheet for proper sample preparation.

Ref.: Hell, J.W., et al. 1995. EMBO J. 14, 3036. Westenbroek, R.E., et al. 1995. J. Neurosci. 15, 6403. Hell, J.W., et al. 1993. J. Cell Biol. 123, 949. Dubel, S.J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 5058. Snutch, T.P. et al. 1991. Neuron 7, 45.