N-(4-Aminobutyl)-2-naphthalenesulfonamide, HCl White solid. PROTECT FROM LIGHT. HYGROSCOPIC. Calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 300 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 260 µM). Purity: ≥97% by TLC. CAS 89108-46-3. Ref.: Tanaka, T., et al. 1983. Pharmacol. 26, 249. Asano, M., et al. 1982. J. Pharmacol. Exp. Ther. 220, 191. Hidaka, H. 1981. Prot. Nuc. Acid Enz. 26, 977. Tanaka, T., and Hidaka, H. 1980. J. Biol. Chem. 255, 11078. |