XeD Clear film. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A reversible, membrane-permeable blocker of IP3-mediated Ca2+ release (IC50 = 648 nM). Also displays high selectivity over the skeletal isoform of the ryanodine receptor type 1 (RyR-1). Purity: ≥90% by TLC. Ref.: Gafni, J., et al. 1997. Neuron 19, 723. Tinker, A., and Williams, A.J. 1995. Biophys. J. 68, 111. Callaway, C., et al. 1994. J. Biol. Chem. 269, 15876. Quirion, J.C., et al. 1992. J. Nat. Prod. 55, 1505. Nakagawa, M., et al. 1984. Tetrahedron Lett. 25, 3227
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