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Kinase Kit Resource

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Inhibitor Database
  InSolution™ Y-27632
Cat. No. 688001  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Rho Kinase (ROCK)

Liquid. A 5 mM (500 µg/296 µl) solution of Y-27632 (Cat. No. 688000) in H2O. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: ≥95% by HPLC.

Ref.: Chitaley, K., et al. 2001. Nat. Med. 7, 119. Davies, S.P., et al. 2000. Biochem. J. 351, 95. Narumiya, S., et al. 2000. Methods Enzymol. 325, 273. Hirose, M., et al. 1999. J. Cell Biol. 141, 1625. Maekawa, M., et al. 1999. Science 285, 895. Uehata, M., et al. 1997. Nature 389, 990.
R: 20/21/22; S: 36
Sold under license of U.S. Patent 4,997,834 and PCT Application W098/06,433A1 and under license from Mitsubishi Pharma Tanabe Corporation.

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EMD Chemicals Inc. list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

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500 µgYN/A

SolubilityMolecular FormulaMol. Wt.
 C14H21N3O · 2HCl · H2338.3 


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688001: InSolution™ Y-27632 - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Rho Kinase (ROCK)

Selected Citations:
  1. James J. Fiordalisi, Patricia J. Keller and Adrienne D. Cox. (2006) PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility. Cancer Research 66, 3153-3161.
  2. Karen E. Porter, et al. (2004) Simvastatin reduces human atrial myofibroblast proliferation independently of cholesterol lowering via inhibition of RhoA. Cardiovascular Research 61, 745-755.
  3. Rick B. Vega, et al. (2004) Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5. Molecular and Cellular Biology 24, 8374-8385.