Z-YVAD-AFC White to off-white solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Fluorogenic caspase-1 substrate. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Purity: 98±1% by HPLC. Excitation max.: ~400 nm, Emission max.: ~505 nm Ac-Tyr-Val-Ala-Asp-AFC Ref.: Jones, R.A., et al. 1998. Hepatology 27, 1632. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Walker, N.P., et al. 1994. Cell 78, 343. Thornberry, N.A., et al. 1992. Nature 356, 768. |
