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| |  | Cat. No. 69050 |
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Specific, sensitive detection of Cre recombinase in cells and cell lysates The Anti-Cre Antibody is a rabbit polyclonal antibody that has high specificity and affinity for bacteriophage P1 Cre recombinase. This preparation can be used to monitor the presence of Cre protein in bacterial and mammalian systems. 
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Varying amounts of purified Cre recombinase were detected by incubation with Anti-Cre Antibody (1:10,000 in TBST), followed by incubation with goat anti-rabbit AP conjugate and color development with NBT/BCIP. S-protein AP conjugate was included in the secondary antibody incubation for detection of Perfect Protein™ Western Markers.
Cre immunostaining in islets of a Cre-expressing transgenic mouse. Cre immunostaining is shown in red (nucleus), insulin immunostaining is shown in green (cytoplasm). Photo courtesy of M.A. Magnuson and T. Jetton, Vanderbilt University School of Medicine.
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| - Jian-Yong Qian, et al. (2008) Reduced cardiac remodeling and function in cardiac-specific EP4 receptor knockout mice with myocardial infarction. Hypertension 51, 560-566.
- B. Dworniczak, et al. (2007) Inducible cre/loxP recombination in the mouse proximal tubule. Nephron Experimental Nephrology 106, e11-e20.
- P Froment, et al. (2007) Inactivation of the IGF-I receptor gene in primary Sertoli cells highlights the autocrine effects of IGF-I. Journal of Endocrinology 194, 557-568.
- Ralph Tiedt, et al. (2007) Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo. Blood 109, 1503-1506.
- Vrushank Davé, et al. (2006) Calcineurin/Nfat signaling is required for perinatal lung maturation and function. Journal of Clinical Investigation 116, 2597-2609.
- Paolo E. Forni, et al. (2006) High levels of cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly. Journal of Neuroscience 26, 9593-9602.
- Fei Gao, et al. (2006) The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Procedings of the National Academy of Science 103, 11987-11992.
- N. Masahira, et al. (2006) Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells.. Developmental Biology 293, 358-369.
- Tarek Rajji, et al. (2006) The Role of CA3 hippocampal NMDA receptors in paired associate learning. Journal of Neuroscience 26, 908-915.
- Qingxia Wei, et al. (2006) High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. Cancer Research 66, 7429-7437.
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