bcl-2 Antagonist Killer

Host: Mouse

Isotype: IgG2a

Immunogen: recombinant human Bak protein from which the C-terminal and transmembrane domains have been deleted

Epitope: within the N-terminal region

Form: Liquid

Formulation: In 0.05 M sodium phosphate buffer, 50% glycerol, pH 7.5.

Preservative: None

Positive Control: HL-60 cells

Comments: Recognizes the ~30 (apparent MW) kDa Bak protein in HL-60 cells.

Ref.: Chittenden, T., et al. 1995. Nature 374, 733. Farrow, S.N., et al. 1995. Nature 374, 731. Kiefer, M.C., et al. 1995. Nature 736. Reed, J.C. 1994. J. Cell Biol. 124, 1. Korsmeyer, S.J., et al. 1993. N. Semin. Cancer Biol. 4, 327.