| Host: Mouse | | Isotype: IgG2a | | Immunogen: a synthetic peptide (QSNRELVVDFLS) corresponding to amino acids 3-14 of human Bcl-xL | | Form: Liquid | | Formulation: In 0.05 M sodium phosphate buffer, 0.2% gelatin, pH 7.5. | | Preservative: ≤0.1% sodium azide | | Positive Control: Doxorubicin-induced MCF7 cells | | Negative Control: trpE (Ab-1) | | Comments: Recognizes the ~34 kDa Bcl-xL protein in doxorubicin-treated MCF-7 cells. | | Ref.: Benito, A., et al. 1997. Leukemia 11, 940. Chang, B.S., et al. 1997. EMBO J. 16, 968. Hsu, Y.T., et al. 1997. Proc. Natl. Acad. Sci USA 94, 3668. Minn, A.J., et al. 1997. Nature 385, 353. Shindler, K.S., et al. 1997. J. Neurosci. 17, 3112. Datta R., et al. 1995. Cell Growth Differ. 6, 363. Fang W., et al. 1995. J. Immunol. 155, 66. Gonzalez-Garcia M., et al. 1994. Development 120, 3033. Krajewski S., et al. 1994. Cancer Res. 54, 5501. Boise L.H., et al. 1993. Cell 74, 597. | |