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  Anti-PARP-1 (Ab-2) Mouse mAb (C-2-10)
Cat. No. AM30  
All Categories » Calbiochem » Antibodies » Primary Antibodies » Polymerases - PARP

Anti-Poly(ADP-Ribose) Polymerase

Host: Mouse
Isotype: IgG1
Immunogen: purified PARP (poly(ADP-ribose) polymerase) from calf thymus
Form: Liquid
Formulation: In PBS, 0.2% BSA.
Preservative: ≤0.1% sodium azide
Positive Control: Etoposide-treated HL-60 cells
Comments: Recognizes the ~116 kDa full-length PARP protein and the ~85 kDa cleaved fragment of PARP in etopside-treated HL-60 cells.
Ref.: Leist, M., et al. 1997. Biochem. Biophys. Res. Commun. 233, 518. Posmantur, R., et al. 1997. J. Neurochem. 68, 2328. Rosen, A., and Casciola-Rosen, L. 1997. J. Cell. Biochem. 64, 50. Rosenthal, D.S., et al. 1997. Exp. Cell. Res. 232, 313. Whitacre, C.M. and Berger, N.A. 1997. Cancer Res. 57, 2157. Shah, G.M., et al. 1996. Biochem. Biophys. Res. Commun. 229,838. Yoshida, S., and Simbulan, C.M. 1994. Mol. Cell Biochem. 138, 39. Satoh, M.S., and Lindahl, T. 1992. Nature 356, 356. Lamarre, D. et al. 1988. Biochem Biophys Acta 95. Berger, N.A. 1985. Radiat. Res. 101, 4.

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100 µgY$264.00


CloneSpecies ReactivityApplication
C-2-10 hamster, human, monkey, mouse, rat 
not chicken 
IB, IF, NOT FS, NOT PS 
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Material Safety Data Sheets:
AM30: Anti-PARP-1 (Ab-2) Mouse mAb (C-2-10) - English
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Related Categories:
All Categories » Calbiochem » Antibodies » Primary Antibodies » Polymerases - PARP

Selected Citations:
  1. Urs Hobom and Matthias Dobbelstein. (2004) E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection. Journal of Virology 78, 7685-7697.
  2. Cecile Tetaud, et al. (2003) Two Distinct Gb3/CD77 Signaling Pathways Leading to Apoptosis are Triggered by Anti-Gb3/CD77 mAb and Verotoxin-1. Journal of Biological Chemistry 278, 45200-45208.
  3. Hendrik Ungefroren, et al. (2001) FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. Journal of Cell Science 114, 2735-2746.
  4. Brian L. Webb, Elsa Jimenez and G. Steven Martin. (2000) v-Src Generates a p53-Independent Apoptotic Signal. Molecular and Cellular Biology 20, 9271-9280.