Anti-RNC-KI | Host: Mouse | | Isotype: IgG2a | | Immunogen: a synthetic peptide (GQTCSVAGWGQTAPLGKHS) corresponding to amino acids 139-157 of human granzyme B | | Form: Liquid | | Formulation: In PBS, 0.2% gelatin, pH 7.4. | | Preservative: ≤0.1% sodium azide | | Positive Control: RNK-16 or YT cells | | Negative Control: HL-60 or CTLL-R8 cells | | Comments: Recognizes the ~32 kDa in human and the ~30 kDa in rat granzyme B protein. Also recognizes higher molecular weight glycosylated forms. | | Ref.: Smyth, M.J. and Trapani, J.A. 1995. Immunology Today 16, 202. Trapani, J.A. et al. 1994. J. Biol. Chem. 269, 18359. Trapani, J.A. et al. 1993. Biochem. Biophys. Res. Comm. 195, 910. Poe, M., et al. 1991. J. Biol. Chem. 266, 98. Tschopp, J. and Nabholz, M. 1990. Annu. Rev. Immunol. 8, 279. Zunino, S.J. et al. 1990. J. Immunol. 144, 2001. Muller-Eberhard, H.J. 1988. Immunol. Rev. 103, 87. Liu, C-C., et al. 1986. J. Exp. Med. 164, 2061. Tschopp, J., et al. 1986. Nature 322, 831. Young, J.D-E. and Cohn, Z.A. 1986. Cell 46, 641. Young, J.D-E., et al. 1986. Science 233, 184. Henkart, P.A. 1985. Annu. Rev. Immunol. 3, 31. Podack, E.R. 1985. Immunol. Today 6, 21. Podack, E.R. and Dennert, G. 1983. Nature 302, 442. | |