Anti-Cleaved CAP4 (Asp³⁸⁴)
Anti-Cleaved CASP8 (Asp³⁸⁴)
Anti-Cleaved FLICE (Asp³⁸⁴)
Anti-Cleaved ICE-LAP5 (Asp³⁸⁴)
Anti-Cleaved MACH (Asp³⁸⁴)
Anti-Cleaved Mch5 (Asp³⁸⁴)

Host: Mouse

Isotype: IgG1

Immunogen: a synthetic peptide corresponding to amino acids near the N-terminus of the p10 subunit of human caspase-8

Form: Liquid

Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5.

Preservative: ≤0.1% sodium azide

Positive Control: Anti-fas treated SKW6.4 cells

Comments: Recognizes the ~10 kDa active subunit of caspase-8. Does not cross-react with full length caspase-8.

Ref.: Niikura, Y., et al. 2002. J. Biochem. 132, 53. Boldin, M.P., et al. 1996. Cell 85, 803. Fernandes-Alnemri, T., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 7464.