Anti-Cleaved APAF-3 (Asp353) Anti-Cleaved CASP9 (Asp353) Anti-Cleaved ICE-LAP6 (Asp353) Anti-Cleaved Mch6 (Asp353) | Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic peptide corresponding to N-terminal amino acids adjacent to the Asp353 cleavage site of rat caspase-9 | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Positive Control: PC-12 cells treated with staurosporine | | Negative Control: Normal rabbit IgG (Cat. No. NI01) | | Comments: Recognizes the ~17 kDa and ~38 kDa forms of the large subunit of activated caspase-9. Does not cross-react with the full length caspase-9 or other cleaved caspases. | | Ref.: Mitchell, K.O., et al. 2000. Cancer Res. 60, 6318. Zou, H., et al. 1999. J. Biol. Chem. 274, 11549. Slee, E.A., et al. 1999. J. Cell Biol. 144, 282. | |